E-I Balance and Human Diseases – from Molecules to Networking
نویسندگان
چکیده
Information transfer in the brain requires a homeostatic control of neuronal excitability. Therefore, a functional balance between excitatory and inhibitory systems is established during development. This review contains recent information about the molecular mechanisms orchestrating the establishment and maintenance of this excitation-inhibition (E-I) balance, and it reviews examples of deregulation of inhibitory and excitatory systems at a molecular, network and disease level of investigation.
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ورودعنوان ژورنال:
- Frontiers in Molecular Neuroscience
دوره 1 شماره
صفحات -
تاریخ انتشار 2008